Rats muscle-tendon interface induced to alcoholic ingestion - DOI: 10.4025/actascibiolsci.v26i3.1601

Abstract

The intake of big amounts of ethylic alcohol can affect many different systems of the human body. In the muscles, alcohol can cause early atrophy, degeneration and motor deficit of muscle fibers, which can cause fiber’s necrosis. In this study we aim at analyzing the influence of ethylic alcohol on the muscle – tendon interface. For it, 12 wistar rats were used (Rattus norvegicus). They were divided in two groups: A (control), treated with potable water and commercial ration and group B (experimental), they received sugar-cane brandy diluted in 30ºG.L. and commercial ration, during 100 days. After sacrifice, the flexor muscles of right anterior paws were collected. They were fixed in Bowin solution for 48 hours and the routines of histological technique was performed for the inclusion in paraffin. As noticed in the methodology used, histological alterations, occurred, such as accumulation of adipose tissue in the interface muscle-tendon region and muscular fiber loss of organization in experimental animals. We can infer that, in the dosage used, the ethylic alcohol causes histological alterations in muscle-tendon interface