<b>Mutagenic effect of contaminated soil on the offspring of exposed rats

  • Edariane Menestrino Garcia Universidade Federal do Rio Grande do Norte
  • Flavio Manoel Rodrigues da Silva Junior Universidade Federal do Rio Grande
  • Ana Luiza Muccillo-Baisch Universidade Federal do Rio Grande

Resumo

This study aimed to measure irreversible DNA damage in the offspring of rats exposed to contaminated soil. Bone marrow cells were removed from the femurs of the offspring of rats that were exposed to contaminated soil via gavage during three different periods: 21 days prior to detection of pregnancy, during pregnancy and 21 days after birth, during the lactation period. For each group, we also had a control group under the same experimental conditions but exposed to uncontaminated soil. The results showed that pups borne of rats exposed to contaminated soil had an increase in the number of micronuclei in the different exposure groups compared with their respective control groups. This suggests a potential risk of mutagenic damage to the offspring of pregnant women who live at the sampling site.

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Biografia do Autor

Edariane Menestrino Garcia, Universidade Federal do Rio Grande do Norte
Universidade Federal do Rio Grande — FURG, Programa de Pós-Graduação em Ciências da Saúde, Faculdade de Medicina.
Publicado
2016-06-08
Como Citar
Garcia, E. M., Silva Junior, F. M. R. da, & Muccillo-Baisch, A. L. (2016). <b&gt;Mutagenic effect of contaminated soil on the offspring of exposed rats. Acta Scientiarum. Health Sciences, 38(1), 19-22. https://doi.org/10.4025/actascihealthsci.v38i1.28545
Seção
Ciências da Saúde

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0.3
2019CiteScore
 
 
8th percentile
Powered by  Scopus