Anabolic-androgenic steroids cycle administration decreases anxious-like behavior but does not affect long-term memory acquisition in rats

Autores

  • Luís Flávio Souza de Oliveira Universidade Federal do Pampa Autor http://orcid.org/0000-0002-5548-6576
  • Miriam Staudt Universidade Comunitária Regional de Chapecó Autor
  • Michel Mansur Machado Universidade Federal do Pampa Autor
  • Alexandre Meneghello Fuentefria Universidade Federal do Rio Grande do Sul Autor

DOI:

https://doi.org/10.4025/actascibiolsci.v41i1.45014

Palavras-chave:

androgens, physical exercise, memory, anxiety

Resumo

The steroid hormones are lipids in nature, which play crucial roles in several metabolic and behavioral pathways in mammals. Drug therapy uses sterol hormones for treating some disturbances linked with its deficiency; however, the illicit use of these hormones by amateur and elite athletes to enhance performance or body appearance may lead to several health issues. In this study we evaluated the anxious-like behavior and the long-term memory acquisition of male rats undergoing sedentary life-style or physical effort, with or without anabolic-androgenic steroids (ASC) treatment. The results showed a decrease in anxious-like behavioral levels in rats that received ASC treatment associated or not with physical effort, but this treatment did not affect the acquisition of long-term memory at the dose and experimental model assessed.

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Biografia do Autor

  • Luís Flávio Souza de Oliveira, Universidade Federal do Pampa
    Graduate Program in Pharmaceutical Sciences
  • Miriam Staudt, Universidade Comunitária Regional de Chapecó
    Pharmacy Department
  • Michel Mansur Machado, Universidade Federal do Pampa
    Graduate Program in Pharmaceutical Sciences

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Publicado

2019-07-22

Edição

Seção

Zoologia

Como Citar

Anabolic-androgenic steroids cycle administration decreases anxious-like behavior but does not affect long-term memory acquisition in rats. (2019). Acta Scientiarum. Biological Sciences, 41(1), e45014. https://doi.org/10.4025/actascibiolsci.v41i1.45014

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