Generating DNA profile from low copy number DNA: Strategies and associated risks

  • Rana Muhammad Mateen University of Management and Technology
  • Asma Tariq University of the Punjab
  • Mureed Hussain University of Management and Technology
Palavras-chave: STR profiling; forensic genetics; likelihood ratio; random match probability.

Resumo

Many shreds of evidence found on the crime scenes contain a trace amount of DNA which results in insignificant profiling results for subsequent comparison. This can nullify the potential evidence material and hamper investigation process. Over the years, different strategies have been employed by various DNA testing laboratories to create interpretable DNA profiles generated from low template of DNA. This review highlights different strategies used by forensic laboratories worldwide for creating complete DNA profiles from low copy number template for comparison purposes along with its associated risks for forensic purposes

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Publicado
2020-07-01
Como Citar
Mateen, R. M., Tariq, A., & Hussain, M. (2020). Generating DNA profile from low copy number DNA: Strategies and associated risks. Acta Scientiarum. Biological Sciences, 42(1), e52239. https://doi.org/10.4025/actascibiolsci.v42i1.52239
Seção
Genética

 

0.6
2019CiteScore
 
 
31st percentile
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0.6
2019CiteScore
 
 
31st percentile
Powered by  Scopus