Efeito mutagênico da água natural (poço, rios Ficha e Minas Gerais, próximos à cidade de Ubiratã, Estado do Paraná, Brasil) em sistema teste animal - DOI: 10.4025/actascibiolsci.v26i1.1665

Maria Fernanda P. Tomasi Baldez da Silva; Gisele Pezente Ferrari; Fabiana de Toledo; Carmem Lucia M. Sartori Cardoso da Rocha; Veronica Elisa Pimenta Vicentini

doi:10.4025/actascibiolsci.v26i1.1665

Mutagenic effect of fresh water (well, rivers Ficha and Minas Gerais, close to the town of Ubiratã, Paraná, Brazil) in the animal test system - DOI: 10.4025/actascibiolsci.v26i1.1665

Maria Fernanda P. Tomasi Baldez da Silva UEM
Gisele Pezente Ferrari UEM
Fabiana de Toledo UEM
Carmem Lucia M. Sartori Cardoso da Rocha UEM
Veronica Elisa Pimenta Vicentini UEM

DOI: https://doi.org/10.4025/actascibiolsci.v26i1.1665

Abstract

Intense industrial development and population growth have been altering the quality of water and innumerous studies have been undertaken to analyze their effects on humans. Due to rivers contamination with agrotoxics, herbicides, pesticides, excess of farming chemical additives and through sewers spilling not properly treated industrial waste, investigating cytotoxic and mutagenic activity of river water becomes all-important. Bone marrow cells of Wistar rats (Rattus norvegicus), treated in vivo, through gavage, in subchronic treatment (7 days), were used as experimental animal test system to investigate the effects of well water and water from the rivers Ficha and Minas Gerais, close to the municipality of Ubiratã, State of Paraná, southern Brazil. Cell division index and metaphase chromosomes were analyzed. The statistical analysis showed that the experiment's water failed to alter cell division cycle of Wistar rats and did not increase number of chromosome aberrations. No cytotoxic and clastogenic effects ensued from this treatment

Downloads

Download data is not yet available.

Author Biography

Veronica Elisa Pimenta Vicentini, UEM

possui graduação em Ciências Biológicas pela Faculdade de Filosofia Ciências e Letras de Ribeirão Preto-USP (1977), Mestrado em Genética pela Faculdade de Medicina de Ribeirão Preto-USP (1984) e Doutorado Em Genética pela Faculdade de Medicina de Ribeirão Preto-USP (1992). Atualmente é Professor Associado C (TIDE) da Universidade Estadual de Maringá-PR. Tem experiência na área de Genética, com ênfase em Efeitos Citogenéticos, Mutagênicos e Antimutagênicos de Plantas Medicinais, Medicamentos Sintéticos e Águas de diferentes fontes, atuando principalmente nos seguintes temas: antimutagênese, mutagênese, citogenética, rato, cebola, plantas medicinais, drogas farmacológicas sintéyicas e águas (mina, poço, rio, efluentes) Currículo Lattes

PDF (Português (Brasil))

Published

2008-04-01

How to Cite

Silva, M. F. P. T. B. da, Ferrari, G. P., Toledo, F. de, Rocha, C. L. M. S. C. da, & Vicentini, V. E. P. (2008). Mutagenic effect of fresh water (well, rivers Ficha and Minas Gerais, close to the town of Ubiratã, Paraná, Brazil) in the animal test system - DOI: 10.4025/actascibiolsci.v26i1.1665. Acta Scientiarum. Biological Sciences, 26(1), 101-105. https://doi.org/10.4025/actascibiolsci.v26i1.1665

Download Citation

Issue

Vol 26 No 1 (2004)

Section

Biology Sciences

DECLARATION OF ORIGINALITY AND COPYRIGHTS

I Declare that current article is original and has not been submitted for publication, in part or in whole, to any other national or international journal.

The copyrights belong exclusively to the authors. Published content is licensed under Creative Commons Attribution 4.0 (CC BY 4.0) guidelines, which allows sharing (copy and distribution of the material in any medium or format) and adaptation (remix, transform, and build upon the material) for any purpose, even commercially, under the terms of attribution.

Read this link for further information on how to use CC BY 4.0 properly.