Avaliação do potencial anti-hiperglicemiante da Pfaffia glomerata (Spreng.) Pedersen (Amaranthaceae)

Neviton Rogerio Sanches; Ricardo Galleto; Carlos Eduardo de Oliveira; Roberto Barbosa Bazotte; Diógenes Aparício Garcia Cortez

doi:10.4025/actascibiolsci.v23i0.2729

Evaluation of antihyperglyicemic potential of Pfaffia glomerata (Spreng.) Pedersen (Amaranthaceae)

Neviton Rogerio Sanches UEM
Ricardo Galleto UEM
Carlos Eduardo de Oliveira UEM
Roberto Barbosa Bazotte UEM
Diógenes Aparício Garcia Cortez UEM

DOI: https://doi.org/10.4025/actascibiolsci.v23i0.2729

Abstract

The roots of Pfaffia glomerata (Spreng.) Pedersen (Amaranthaceae), commonly known as Brazilian ginseng, are used in folk medicine as a tonic and as an aphrodisiac and antidiabetic medicine. The methanolic extract and its fractions obtained from roots were used to evaluate their antihyperglycemic potential in male Wistar rats. While the methanolic extract yielded four fractions, the butanolic extract had larger antihyperglycemic potential, starting from 50 mg/kg. No activity was shown by its fractionation. The β-ecdisone identified in the butanolic extract is not related with the antihyperglycemic effect

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Author Biography

Diógenes Aparício Garcia Cortez, UEM

Possui graduação em Farmácia Bioquímica pela Universidade de São Paulo (1974), mestrado em Química pela Universidade Federal de São Carlos (1988) e doutorado em Química pela Universidade Federal de São Carlos (1993). Pós-Doutorado em farmacognosia na Universite de Lausanne (Suiça) (1997). Atualmente é professor Associado da Universidade Estadual de Maringá, departamento de farmácia e farmacologia. Tem experiência na área de Farmácia, com ênfase em Farmacognosia, atuando principalmente nos seguintes temas: fitoquímica, controle de qualidade, validação de fitoterápicos, antimicrobianos, kielmeyera coriacea, xantonas, atividades biológicas e piperaceae Currículo Lattes

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Published

2008-05-09

How to Cite

Sanches, N. R., Galleto, R., Oliveira, C. E. de, Bazotte, R. B., & Cortez, D. A. G. (2008). Evaluation of antihyperglyicemic potential of Pfaffia glomerata (Spreng.) Pedersen (Amaranthaceae). Acta Scientiarum. Biological Sciences, 23, 613-617. https://doi.org/10.4025/actascibiolsci.v23i0.2729

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Issue

Vol 23 (2001)

Section

Biology Sciences

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