Biological effects of <em>Pfaffia glomerata</em> (Spreng.) Pedersen and <em>Pfaffia paniculata</em> (Martius) Kuntze (Amaranthaceae)

  • Nádia Regina Alvim UEM
  • Kely Christiane Tavares da Cunha UEM
  • Lúcia Eliane Ranieri Cortez UNIPAR
  • Roberto Barbosa Bazotte UEM
  • Luis Carlos Marques UEM
  • Diógenes Aparício Garcia Cortez UEM

Abstract

Pfaffia glomerata (Spreng.) Pedersen. (Amaranthaceae) and Pfaffia paniculata (Martius) Kuntze are native plants found in the flooded area of the islands of Porto Rico, state of Paraná, Brazil. They are used in folk medicine as tonics, aphrodisiacs, and to treat diabetes. The methanolic extract obtained from roots of both species was used to evaluate the molluscicidal activity against the periwinkle Biomphalaria glabrata and the hypoglycemic activity of Pfaffia glomerata was investigated in rats with diabetes induced by alloxan. The saponins from the methanolic extract of P. glomerata and P. paniculata were analyzed by thin-layer chromatography and scum and the hemolitic index was measured. The methanolic extract obtained from Pfaffia glomerata showed higher content of hemolytic saponin than Pfaffia paniculata and presented molluscicidal activity against Biomphalaria glabrata from 200 ppm. However, the treatment with P. glomerata extract did not promote any significant effect on glycemic levels.

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Author Biography

Diógenes Aparício Garcia Cortez, UEM
Possui graduação em Farmácia Bioquímica pela Universidade de São Paulo (1974), mestrado em Química pela Universidade Federal de São Carlos (1988) e doutorado em Química pela Universidade Federal de São Carlos (1993). Pós-Doutorado em farmacognosia na Universite de Lausanne (Suiça) (1997). Atualmente é professor Associado da Universidade Estadual de Maringá, departamento de farmácia e farmacologia. Tem experiência na área de Farmácia, com ênfase em Farmacognosia, atuando principalmente nos seguintes temas: fitoquímica, controle de qualidade, validação de fitoterápicos, antimicrobianos, kielmeyera coriacea, xantonas, atividades biológicas e piperaceae Currículo Lattes
Published
2008-07-17
How to Cite
Alvim, N. R., Cunha, K. C. T. da, Cortez, L. E. R., Bazotte, R. B., Marques, L. C., & Cortez, D. A. G. (2008). Biological effects of <em>Pfaffia glomerata</em> (Spreng.) Pedersen and <em>Pfaffia paniculata</em&gt; (Martius) Kuntze (Amaranthaceae). Acta Scientiarum. Biological Sciences, 21, 349-352. https://doi.org/10.4025/actascibiolsci.v21i0.4441
Section
Biology Sciences

 

0.6
2019CiteScore
 
 
31st percentile
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0.6
2019CiteScore
 
 
31st percentile
Powered by  Scopus