<b>Evaluation of the tickcide, genotoxic, and mutagenic effects of the <i>Ruta graveolens</i> L. (Rutaceae)

  • Alessandra Vargas de Carvalho Universidade Federal do Pampa
  • Irina Lübeck Universidade Federal do Pampa
  • Mariana Balhego da Rocha Universidade Federal do Pampa
  • Camila Martins Güez Universidade Federal do Pampa
  • Michel Mansur Machado Universidade Federal do Pampa
  • Luís Flávio Souza de Oliveira Universidade Federal do Pampa

Resumo

Current analysis investigated the tickcide effects of the aqueous extract and chloroform fractions of Ruta graveolens L. (rue) on engorged females of Rhipicephalus microplus, as well as their genotoxic and mutagenic effects on human leukocytes. The best tickcide activity (non-dependent dose) and genotoxic / mutagenic effects (dependent-dose) were observed on exposure to chloroform fractions. Results suggest that extract fractions of R. graveolens L are efficient against R. microplus, although the fraction and the tested concentrations show genotoxic and mutagenic potential for human leukocytes.



 

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Publicado
2015-10-01
Como Citar
Carvalho, A. V. de, Lübeck, I., Rocha, M. B. da, Güez, C. M., Machado, M. M., & Oliveira, L. F. S. de. (2015). <b>Evaluation of the tickcide, genotoxic, and mutagenic effects of the <i>Ruta graveolens</i&gt; L. (Rutaceae). Acta Scientiarum. Biological Sciences, 37(4), 491-497. https://doi.org/10.4025/actascibiolsci.v37i4.27576
Seção
Morfofisiologia Animal

 

0.6
2019CiteScore
 
 
31st percentile
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0.6
2019CiteScore
 
 
31st percentile
Powered by  Scopus