Valores de referência de alguns parâmetros fisiológicos de ratos do Biotério Central da Universidade Estadual de Maringá, Estado do Paraná - DOI: 10.4025/actascihealthsci.v28i2.1099

Jailson Araújo Dantas; Celia Regina Ambiel; Roberto Kenji Nakamura Cuman; Silmara Baroni; Ciomar Aparecida Bersani Amado

doi:10.4025/actascihealthsci.v28i2.1099

Reference values of some physiological parameters in the rats of the Central Biotery at the State University of Maringá, State of Paraná - DOI: 10.4025/actascihealthsci.v28i2.1099

Authors

Jailson Araújo Dantas UEM Author
Celia Regina Ambiel UEM Author
Roberto Kenji Nakamura Cuman UEM Author
Silmara Baroni UEM Author
Ciomar Aparecida Bersani Amado Editor - UEM Author

DOI:

https://doi.org/10.4025/actascihealthsci.v28i2.1099

Keywords:

ratos, análise bioquímica plasmática, perfil hematológico, parâmetros urinários

Abstract

The present work was carried out to establish reference values for some physiological parameters (biochemical, hematological and urinary) in rats proceeding from the Central Biotery at the State University of Maringá, State of Paraná. Normal male Wistar rats weighing 200-220 g were used. The hematological profile (total leukocytes, mononuclear and polymorphonuclear cells count), the clinic chemistry (aspartate aminotransferase, alanine aminotransferase, glucose, creatinine, alkaline phosphatase, acid phosphatase, urea, cholesterol, HDL-c, triglycerides, glucose tolerance) and urinary parameters (glucose and creatinine) were determined. Each laboratory should establish a database of reference values for their animals, according to diet, strain, sex and age for each species used. Thus, in this work, a database is provided regarding reference values of some physiological parameters in rats for use in experimental investigations

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Author Biography

Ciomar Aparecida Bersani Amado, Editor - UEM

possui graduação em Biomedicina (1975), mestrado em Farmacologia pela Faculdade de Medicina de Ribeirão Preto-USP (1982) e doutorado em Farmacologia pelo Instituto de Ciências Biomédicas-USP/SP (1989). Atualmente é Professora Associado da Universidade Estadual de Maringá. É docente dos Programas de Pós-graduação nas áreas de Ciências Farmacêuticas e Ciências Biológicas. Realiza trabalhos na área de Farmacologia, atuando principalmente nos seguintes temas: inflamação, antiinflamatório, diabetes, produtos naturais e toxicidade. Currículo Lattes

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Published

2008-03-13

Issue

Vol. 28 No. 2 (2006)

Section

Pharmacy

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How to Cite

Reference values of some physiological parameters in the rats of the Central Biotery at the State University of Maringá, State of Paraná - DOI: 10.4025/actascihealthsci.v28i2.1099. (2008). Acta Scientiarum. Health Sciences, 28(2), 165-170. https://doi.org/10.4025/actascihealthsci.v28i2.1099