<b>The effect of morphine on vagal inhibition of the heart: demonstration of dual atrioventricular nodal pathways</b> - DOI: 10.4025/actascihealthsci.v28i2.1102

  • José Geraldo Pereira da Cruz FURB

Abstract

That electrical stimulation of the vagus decreased heart rate and increased the PQ interval in electrocardiogram, consistent with anterograde dual atriventricular conduction. The present experiments were investigating the interaction of the morphine with cardiac parasympathetic nervous control in dual atrioventricular node. Electrical stimulation of the vagus nerve induced significant bradycardia and of third degree atrioventricular block and the P wave appearance was negative in leads II. Because background anesthesia modulates the heart, administered morphine injection the P waves appearance was positive through one inhibitory action on atrioventricular nodal reentry. All suggest the presence of two functionally and anatomically distinct atrioventricular pathways

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Author Biography

José Geraldo Pereira da Cruz, FURB
possui graduação em Ciências Biológicas pela Pontifícia Universidade Católica de Campinas (1979) , especialização em Metodologia do Ensino Superior pelo Fundação Universidade Regional de Blumenau (1998) , especialização em Biologia Geral pela Universidade de Brasília (1979) e mestrado em Farmacologia pela Universidade Federal de Santa Catarina (1996) . Atualmente é funcionário do Fundação Universidade Regional de Blumenau. Tem experiência na área de Farmacologia , com ênfase em Neuropsicofarmacologia. Atuando principalmente nos seguintes temas: Poliaminas, Ansiedade, Labirinto em cruz elevado Currículo Lattes
Published
2008-03-13
How to Cite
Pereira da Cruz, J. G. (2008). <b>The effect of morphine on vagal inhibition of the heart: demonstration of dual atrioventricular nodal pathways</b&gt; - DOI: 10.4025/actascihealthsci.v28i2.1102. Acta Scientiarum. Health Sciences, 28(2), 171-174. https://doi.org/10.4025/actascihealthsci.v28i2.1102
Section
Pharmacy

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0.3
2019CiteScore
 
 
8th percentile
Powered by  Scopus