Imunoestimuladores - potencial para o tratamento de imunodepressões e doenças infecciosas

Sandra Cristina Barão; Selma Giordio

doi:10.4025/actascihealthsci.v20i0.4482

Immunostimulants - potential for immunodepression and treatment of infectious diseases

Sandra Cristina Barão UNICAMP
Selma Giordio UNICAMP

DOI: https://doi.org/10.4025/actascihealthsci.v20i0.4482

Abstract

The agents that restore and enhance the ability of the immune system to react to a myriad of pathogens and tumors and increase the immunogenicity of vaccines are discussed in this article. The several pathological conditions which are caused by inadequate functioning of the immune system such as congenital and acquired immunodeficiences (dramatically exemplified by AIDS) have brought immunostimulation into focus. Many different types of compounds have been demonstrated to possess immunostimulatory properties. The rich arsenal of endogenous molecules together with natural and synthetic exogenous compounds are here described. Special emphasis has been given to the origin, chemical structure and main immunologic activities of two immunomodulators, products of bacterial origin and derived from nucleic acids. An attempt is made to envisage the future of these pharmacological agents with an emphasis on their potential medical usefulness.

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Author Biography

Selma Giordio, UNICAMP

Possui graduação em Ciencias Biologicas pela Universidade Estadual de Campinas (1983), mestrado em Imunologia pela Universidade de São Paulo (1989) e doutorado em Ciências Biológicas (Imunologia e Biologia Molecular) pela Universidade Federal de São Paulo (1993). Atualmente é professora associada no Instituto de Biologia da Universidade Estadual de Campinas com bolsa de produtivade do CNPq. Tem experiência na área de Parasitologia, com ênfase em Protozoologia de Parasitos, atuando principalmente nos seguintes temas: leishmania, macrófagos, leishmaniose, imunoestimuladores, oxigenação hiperbárica e hipóxia Currículo Lattes

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Published

2008-07-21

How to Cite

Barão, S. C., & Giordio, S. (2008). Immunostimulants - potential for immunodepression and treatment of infectious diseases. Acta Scientiarum. Health Sciences, 20, 235-241. https://doi.org/10.4025/actascihealthsci.v20i0.4482

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Issue

Vol 20 (1998)

Section

Health Sciences

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