<b>Prevalence of variant hemoglobins and thalassemias in a maroon community in Sergipe, Brazil

  • Elizano Santos de Assis Universidade Tiradentes
  • Jamille Alves Araújo Universidade Tiradentes
  • Maria Izabel Ribeiro Cabral de Rezende Universidade Tiradentes
  • Cristiane Costa da Cunha Oliveira Universidade Tiradentes
  • Francisco Prado Reis Universidade Tiradentes
  • Cláudia Moura de Melo Universidade Tiradentes

Resumen

Current analysis investigates the sickle-cell syndrome among members of a maroon community (comunidade quilombola) in the state of Sergipe, Brazil. The entire population, comprising five hundred and ninety-three people, was screened. Blood samples were collected from 318 people, aged between six months and fifty years, who underwent a solubility test to assess the presence of HbS, followed by Sickle-Cell Test to confirm its presence. Results revealed that 2.2% of the three hundred and eighteen people tested have hemoglobin HbS in their blood; 57% have type HbAS and 43% have a combination between thalassemia and heterozygous with a variable percentage of HbS ranging between 24.9 and 37.9%. Blood sampling revealed that only five out of the 318 people belonged to different families. Results are highly relevant for public health policies on the sickle-cell syndrome and its management.

 

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Biografía del autor/a

Elizano Santos de Assis, Universidade Tiradentes
Nurse. Master in Health and the Environment by Tiradentes University (UNIT ), Assistant Professor I, Department of Nursing, Tiradentes University (UNIT )
Jamille Alves Araújo, Universidade Tiradentes
Odontologist. Master in Health and the Environment Tiradentes University (UNIT ), Institute of Technology and Research ( ITP )
Maria Izabel Ribeiro Cabral de Rezende, Universidade Tiradentes
Nurse. Student of the Graduate Program in Health and Environment Tiradentes University (UNIT ) Program
Cristiane Costa da Cunha Oliveira, Universidade Tiradentes
Odontologist. PhD in Public Health from the University of Pernambuco. Researcher of LPPS - ITP, Tiradentes University (UNIT). Professor, Master of Health and Environment , University Tiradentes (UNIT )
Francisco Prado Reis, Universidade Tiradentes
Medical. Postdoctoral Fellow in Biological Sciences at the Pasteur Institute in Lyon - France, Professor, Faculty of Medicine, Tiradentes University (UNIT)
Cláudia Moura de Melo, Universidade Tiradentes
Biologist. PhD in Parasitology from the State University of Campinas - UNICAMP , Full Professor I (DSP I) Program Postgraduate Health and Environment , Tiradentes University (UNIT ), coordinator of the Laboratory of Molecular Biology of the ITP - LPPS Tiradentes University (UNIT )
Publicado
2015-07-01
Cómo citar
Assis, E. S. de, Araújo, J. A., Rezende, M. I. R. C. de, Oliveira, C. C. da C., Reis, F. P., & Melo, C. M. de. (2015). <b&gt;Prevalence of variant hemoglobins and thalassemias in a maroon community in Sergipe, Brazil. Acta Scientiarum. Health Sciences, 37(2), 211-216. https://doi.org/10.4025/actascihealthsci.v37i2.23444
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8th percentile
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0.3
2019CiteScore
 
 
8th percentile
Powered by  Scopus