Global stability of a fractional virus infection model in the presence of humoral immunity and two classes of infected cell
Global stability of a fractional virus infection model
Resumen
It is well known that the benefit of fractional differentiation makes strong utility to model natural realities with vast range
memory, hereditary properties, and viral infections such as SARS, COVID, HIV, and Dengue fever. According to biological evidence,
complicated systems are more inclined to stability in comparison to simple systems, so in this article, we focused on a fractional derivative order system. Adequate qualifications for the global steady state of stationary points of a Caputo fractional derivative order system with Beddington-DeAngelis functional response will be obtained by using Lyapunov's method and LaSalle's invariance principle. We prove the global stability of the equilibria of the system by the values of the primary reproductive number $({B_r})$ and the reproductive number for humoral immune response $(R_{H})$ as a natural reaction of antibodies. We support the analytical results through numerical simulations.
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Derechos de autor 2025 Boletim da Sociedade Paranaense de Matemática
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