Temas de Tecnologia Farmacêutica
Abstract
Theme 1: Traditional Chinese Medicine Plants: Stability studies are carried out after the development of a new formulation, in order to predict, determine or monitor its shelf life. Accelerated stability studies are designed to accelerate the chemical degradation and/or physical changes of a pharmaceutical product under forced storage conditions. Traditional Chinese Medicine, included in the SUS since 2006, is based on the division of the universe into two principles: yin and yang, which are subdivided into phases of regulation, and it is these phases that keep the body in balance.
Theme 2:
STUDY OF THE RHEOLOGICAL BEHAVIOR OF DERMAL FILLERS AT DIFFERENT TEMPERATURES
Hyaluronic Acid (HA) fillers are the most popular and performed aesthetic procedures in the world. They are composed of biocompatible biopolymers, and are widely used for hydration, increasing facial volume and wrinkle correction. Several brands of fillers are currently available on the market, and their rheological characteristics are extremely variable. Rheology is an area of physics that study the deformation of a sample under the influence of stresses. It is extremely important to differentiate characteristics as the extrusion of the filler from the syringe and its in vivo degradation.
Topic 3: DENTAL FILMS CONTAINING MICROPARTICLES OF PLANT EXTRACT FOR THE TREATMENT OF PERIODONTAL DISEASES
Periodontal diseases are among the most common in the world, including periodontitis, becoming increasingly serious. Among the various etiological factors of the disease, in addition to poor oral hygiene, smoking, bacterial infections in the periodontium and genetic factors stand out. Limonium brasiliense, known as baicuru, is a plant that has bacteriostatic, antioxidant, antiviral and anti-inflammatory activity, demonstrating great potential in the treatment of periodontitis.
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References
Faivre J, Gallet M, Tremblais E, Trévidic P, Bourdon F. Advanced Concepts in Rheology for the Evaluation of Hyaluronic Acid-Based Soft Tissue Fillers. Dermatol Surg. 2021 May 1;47(5):e159-e167.
Zerbinati N, Sommatis S, Maccario C, Capillo MC, Grimaldi G, Alonci G, et al. Toward Physicochemical and Rheological Characterization of Different Injectable Hyaluronic Acid Dermal Fillers Cross-Linked with Polyethylene Glycol Diglycidyl Ether. Polymers (Basel). 2021 Mar 19;13(6):948.
Zerbinati N, Capillo MC, Sommatis S, Maccario C, Alonci G, Rauso R, et al. Rheological Investigation as Tool to Assess Physicochemical Stability of a Hyaluronic Acid Dermal Filler Cross-Linked with Polyethylene Glycol Diglycidyl Ether and Containing Calcium Hydroxyapatite, Glycine and L-Proline. Gels. 2022 Apr 23;8(5):264.

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