Avaliação do potencial anti-hiperglicemiante da Pfaffia glomerata (Spreng.) Pedersen (Amaranthaceae)

Neviton Rogerio Sanches; Ricardo Galleto; Carlos Eduardo de Oliveira; Roberto Barbosa Bazotte; Diógenes Aparício Garcia Cortez

doi:10.4025/actascibiolsci.v23i0.2729

Evaluation of antihyperglyicemic potential of Pfaffia glomerata (Spreng.) Pedersen (Amaranthaceae)

Authors

Neviton Rogerio Sanches UEM Author
Ricardo Galleto UEM Author
Carlos Eduardo de Oliveira UEM Author
Roberto Barbosa Bazotte UEM Author
Diógenes Aparício Garcia Cortez UEM Author

DOI:

https://doi.org/10.4025/actascibiolsci.v23i0.2729

Keywords:

Pfaffia glomerata, Amaranthaceae, antihiperglicemiante, beta-ecdisona

Abstract

The roots of Pfaffia glomerata (Spreng.) Pedersen (Amaranthaceae), commonly known as Brazilian ginseng, are used in folk medicine as a tonic and as an aphrodisiac and antidiabetic medicine. The methanolic extract and its fractions obtained from roots were used to evaluate their antihyperglycemic potential in male Wistar rats. While the methanolic extract yielded four fractions, the butanolic extract had larger antihyperglycemic potential, starting from 50 mg/kg. No activity was shown by its fractionation. The β-ecdisone identified in the butanolic extract is not related with the antihyperglycemic effect

Downloads

Download data is not yet available.

Author Biography

Diógenes Aparício Garcia Cortez, UEM

Possui graduação em Farmácia Bioquímica pela Universidade de São Paulo (1974), mestrado em Química pela Universidade Federal de São Carlos (1988) e doutorado em Química pela Universidade Federal de São Carlos (1993). Pós-Doutorado em farmacognosia na Universite de Lausanne (Suiça) (1997). Atualmente é professor Associado da Universidade Estadual de Maringá, departamento de farmácia e farmacologia. Tem experiência na área de Farmácia, com ênfase em Farmacognosia, atuando principalmente nos seguintes temas: fitoquímica, controle de qualidade, validação de fitoterápicos, antimicrobianos, kielmeyera coriacea, xantonas, atividades biológicas e piperaceae Currículo Lattes

Downloads

PDF (Portuguese)

Published

2008-05-09

Issue

Vol. 23 (2001)

Section

Biology Sciences

License

DECLARATION OF ORIGINALITY AND COPYRIGHTS

I Declare that current article is original and has not been submitted for publication, in part or in whole, to any other national or international journal.

The copyrights belong exclusively to the authors. Published content is licensed under Creative Commons Attribution 4.0 (CC BY 4.0) guidelines, which allows sharing (copy and distribution of the material in any medium or format) and adaptation (remix, transform, and build upon the material) for any purpose, even commercially, under the terms of attribution.

Read this link for further information on how to use CC BY 4.0 properly.

How to Cite

Evaluation of antihyperglyicemic potential of Pfaffia glomerata (Spreng.) Pedersen (Amaranthaceae). (2008). Acta Scientiarum. Biological Sciences, 23, 613-617. https://doi.org/10.4025/actascibiolsci.v23i0.2729