The effect of obesity on spirometric parameters in adolescents subjected to exercise bronchoprovocation - DOI: 10.4025/actascihealthsci.v32i1.6476

Abstract

The objective of this study was to evaluate the effect of obesity on spirometric parameters in adolescents subjected to a physical exercise bronchoprovocation test. It was a cross-sectional, descriptive and correlational study composed of 15 adolescents of both genders. The diagnosis of asthma was made by clinical history and ISAAC questionnaire, and obesity by BMI above the 95^th percentile. The bronchoprovocation test with physical exercise was used for assessment of exercise induced asthma (EIA), considering positive a decrease in forced expiratory volume in one second (FEV₁) > 10% of pre-exercise, and the intensity was calculated by the EIA maximum percentage fall in FEV₁ (% Fall_max FEV₁). We used the independent t test or Mann-Whitney U test and the Spearman rho correlation (p < 0.05). Significant differences were found between asthmatics and non-asthmatics to % Fallmax FEV₁ (p = 0.034). There was a negative moderate relationship to Fall_max FEV₁ with leukocytes, and % Fall_max FEV₁ with leukocytes. It can be concluded that the spirometric variables presented moderated correlation with the systemic inflammation of obesity.