Determinação de ferro (III) em produtos farmacêuticos por titulação fotométrica - doi: 10.4025/actascihealthsci.v33i1.8034

Airton Vicente Pereira; Natalício Valus; Flávio Luís Beltrame; Lúcia Helena Garrido

doi:10.4025/actascihealthsci.v33i1.8034

Determination of iron (III) in pharmaceutical products by photometric titration - doi: 10.4025/actascihealthsci.v33i1.8034

Authors

Airton Vicente Pereira UEPG Author
Natalício Valus UEPG Author
Flávio Luís Beltrame UEPG Author
Lúcia Helena Garrido UEPG Author

DOI:

https://doi.org/10.4025/actascihealthsci.v33i1.8034

Keywords:

photometric titration, iron (III), pharmaceutical preparations

Abstract

This paper describes a simple, precise and low-cost photometric titration method for iron (III) determination in pharmaceutical preparations. The photometric titration system was constructed using the peristaltic pump of a conventional spectrophotometer. The method is based on titration of iron (III) with EDTA using salicylic acid as indicator. The absorption of the iron (III)-salicylic acid complex was monitored spectrophotometrically at 525 nm. The limit of quantification was 5 µg of iron (III). The photometric titration procedure was applied for the determination of iron (III) in samples of ferrous sulfate and ferric hydroxide polymaltose complex. The procedure showed sensibility, reproducibility and accuracy for use as a method for the routine analysis of iron (III) in pharmaceutical formulations.

Downloads

Download data is not yet available.

Author Biographies

Airton Vicente Pereira, UEPG

Universidade Estadual de Ponta Grossa Departamento de Ciências Farmacêuticas Laboratório de Quimica Farmacêutica
Natalício Valus, UEPG

Universidade Estadual de Ponta Grossa Acadêmico de Iniciação Científica Progrma PIBIC/CNPQ/UEPG
Flávio Luís Beltrame, UEPG

Universidade Estadual de Ponta Grossa Departamento de Ciências Farmacêuticas Laboratório de Tecnologia Farmacêutica
Lúcia Helena Garrido, UEPG

Universidade Estadual de Ponta Grossa Departamento de Química Laboratório de Ensino de Quimica

Downloads

PDF (Portuguese)

Published

2011-05-18

Issue

Vol. 33 No. 1 (2011)

Section

Pharmacy

License

DECLARATION OF ORIGINALITY AND COPYRIGHTS

I Declare that current article is original and has not been submitted for publication, in part or in whole, to any other national or international journal.

The copyrights belong exclusively to the authors. Published content is licensed under Creative Commons Attribution 4.0 (CC BY 4.0) guidelines, which allows sharing (copy and distribution of the material in any medium or format) and adaptation (remix, transform, and build upon the material) for any purpose, even commercially, under the terms of attribution.

Read this link for further information on how to use CC BY 4.0 properly.

How to Cite

Pereira, A. V., Valus, N., Beltrame, F. L., & Garrido, L. H. (2011). Determination of iron (III) in pharmaceutical products by photometric titration - doi: 10.4025/actascihealthsci.v33i1.8034. Acta Scientiarum. Health Sciences, 33(1), 65-70. https://doi.org/10.4025/actascihealthsci.v33i1.8034