Deficiência de vitamina D e mortalidade cardiovascular na doença renal crônica: revisão integrativa
Resumo
Objetivo: analisar os estudos científicos desenvolvidos sobre a deficiência de vitamina D e a mortalidade por causa cardiovascular nas pessoas com doença renal crônica. Método: Trata-se de uma revisão integrativa da literatura a partir das bases de dados LILACS, PubMed, Medline e na biblioteca eletrônica SciELO, utilizando os descritores deficiência de vitamina D, mortalidade cardiovascular e doença renal crônica, sendo selecionados 14 artigos para análise. Resultados: A partir da análise dos artigos selecionados, foi possível identificar que a deficiência de vitamina D e a mortalidade cardiovascular são condições muito frequentes em renais crônicos e, por isso, discutem-se hipóteses de que a correção desta deficiência pode exercer efeitos benéficos sobre a doença e mortalidade cardiovascular nessa população. Conclusão: Há uma intrínseca relação entre a carência de vitamina D e a mortalidade cardiovascular. Entretanto, ainda é discutível se a suplementação de vitamina D reduz a mortalidade cardiovascular nos doentes renais crônicos. Tal hipótese precisa ser testada em ensaios clínicos, ensejando a necessidade de se desenvolver mais pesquisas sobre o tema.
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