Deficiencia de vitamina D y mortalidad cardiovascular en la enfermedad renal crónica: revisión integradora
Resumen
Objetivo: analizar los estudios científicos desarrollados sobre la deficiencia de vitamina D yla mortalidad por causa cardiovascular en las personas conenfermedad renal crónica. Método: se trata de una revisión integradora de la literatura a partir de las bases de datos LILACS, PubMed, Medline yen la biblioteca electrónica SciELO, utilizando los descriptores deficiencia de vitamina D; mortalidad cardiovascular yenfermedad renal crónica, siendo seleccionados 14 artículos para el análisis. Resultados: a partir del análisis de los artículos seleccionados, fue posible identificar que la deficiencia de vitamina D yla mortalidad cardiovascular son condiciones muy frecuentes en enfermos renales crónicos y, por ello, se discuten hipótesis de que la corrección de esta deficiencia puede ejercer efectos benéficos sobre la enfermedady mortalidad cardiovascular enesta población. Conclusión: hay una intrínseca relación entre la carencia de vitamina D yla mortalidad cardiovascular. Sin embargo, aúnes discutible sila suplementación de vitamina D reducela mortalidad cardiovascular en los enfermos renales crónicos. Tal hipótesisnecesita ser probada en ensayos clínicos, fomentando la necesidad de desarrollarse más investigaciones sobre el tema.
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