Effects of HeNe 632.8nm laser application on wound healing in rats

  • Delcides Gomes Nascimento UEL
  • Carlos Alexandre Molena-Fernandes UEL
  • Juliano Luiz Sartoretto Harvard
  • Luiz Carlos Bruschi UEL
  • Roberto Kenji Nakamura Cuman UEM
  • Francisco Pereira Silva UEL
DOI: https://doi.org/10.4025/ciencuidsaude.v5i2.5081
Keywords: Laser Therapy, Wound healing, HeNe 532.8nm laser, Fibroblasts.

Abstract

The aim of this study was to investigate the effects of HeNe 632.8nm laser on fibroblast content and its influence on the wound healing process in rats. After a deliberate incision, the animals were subjected to irradiation with HeNe laser 632.8nm (4J/cm², once a day) for periods of 1,2,3,4,5,7,9,11,15,21 and 29 days. The histological analysis and fibroblasts count were analyzed using Image Pro Plus 5 imaging software. HeNe laser irradiation promoted a decrease in the fibroblast content in the irradiated wound area, suggesting an increase in collagen synthesis and fibroblasts differentiation. The data indicated that irradiation with HeNe 632.8nm interferes in the wound healing process.

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Published
2008-09-16
How to Cite
Nascimento, D. G., Molena-Fernandes, C. A., Sartoretto, J. L., Bruschi, L. C., Cuman, R. K. N., & Silva, F. P. (2008). Effects of HeNe 632.8nm laser application on wound healing in rats. Ciência, Cuidado E Saúde, 5(2), 229-235. https://doi.org/10.4025/ciencuidsaude.v5i2.5081
Issue
Vol 5 No 2 (2006)
Section
Original articles