Spatio-temporal evolution of gestational and congenital syphilis in the state of Paraná

Keywords: Spatial Analysis, Sexually Transmitted Infections, Nursing, Syphilis, Maternal and Child Health

Abstract

Objective: to compare sociodemographic characteristics, distribution and spatial association of gestational and congenital syphilis in Paraná in 2008 and 2018. Methods: ecological study with cases of gestational syphilis (GS) and congenital syphilis (CS) reported in the years 2008 and 2018 in the Information System of Notifiable Diseases of the State of Paraná. Data were analyzed through descriptive analysis, distribution and spatio-temporal association, using techniques called Getis-Ord General G and Getis-Ord Gi*. Results: GS increased from 194 cases in 2008 to 2,828 in 2018, and CS from 85 cases to 880 in 2018, mainly among pregnant women of white race/color and aged between 20 and 39 years. In 2008, there were more diagnoses among women with less than eight years of study and primary clinical classification. In 2018, with more than eight years of study and latent clinical classification. For CS, in both years, predominated children of white race/ color, age group up to six days of life and recent CS. The spatio-temporal analysis showed a higher prevalence in the East and West macro-regions of the state of Paraná. Conclusions: The lower the educational level, the greater the probability for the development of the disease among pregnant women and, consequently, for their children. The profile of pregnant women and the spaces of greater occurrence favor the planning and execution of localized actions for diagnosis and health education.

Downloads

Download data is not yet available.

Author Biographies

Milena Passarelli Cortez, State University of Londrina

Nurse. Resident in Obstetric Nursing. Department of Nursing. State University of Londrina. Londrina, Paraná, Brazil.

Alessandro Rolim Scholze, State University of the North of Paraná

Nurse. Doctor in Nursing. Department of Nursing. State University of the North of Paraná (UENP). Bandeirantes, Paraná, Brazil.

Rosana Rosseto de Oliveira, State University of Maringá

Nurse. Doctor in Nursing. Postgraduate Program in Nursing. State University of Maringá. Maringá, Paraná, Brazil.

Ricardo Castanho Moreira, State University of the North of Paraná

Nurse. Doctor in Nursing. Department of Nursing. State University of the North of Paraná (UENP). Bandeirantes, Paraná, Brazil.

Kelly Holanda Prezotto Araújo, Midwestern State University

Nurse. Doctor in Nursing. Department of Nursing. Midwestern State University. Guarapuava, Paraná, Brazil.

Emiliana Cristina Melo, State University of the North of Paraná

Nurse. Doctor in Nursing. Department of Nursing. State University of the North of Paraná (UENP). Bandeirantes, Paraná, Brazil.

References

Kojima N, Klausner JD. An Update on the Global Epidemiology of Syphilis. Curr Epidemiol Rep. 2018. 5:24–38. DOI: 10.1007/s40471-018-0138-z

Brasil. Ministério da Saúde (BR), Secretaria de Vigilância em Saúde. Boletim Epidemiológico: Sífilis [Internet]. Brasília: Ministério da Saúde; 2020. Disponível em: https://www.gov.br/aids/pt-br/centrais-de-conteudo/boletins-epidemiologicos/2020/sifilis/boletim_sifilis_2020.pdf/view. Acesso em: 15 jan, 2021.

Taylor MM, Nurse-Findlay S, Zhang X, Hedman L, Kamb ML, Broutet N, Kiarie J. Estimating Benzathine Penicillin Need for the Treatment of Pregnant Women Diagnosed with Syphilis during Antenatal Care in High-Morbidity Countries. PLoS One. 2016;11(7):e0159483. DOI: 10.1371/journal.pone.0159483

World Health Organization. Guidelines for the treatment of Treponema pallidum (syphilis). Geneva: WHO; 2016. Disponível em: https://www.who.int/publications/i/item/9789241549714. Acesso em: 17 nov, 2022.

Conceição HN, Câmara JT, Pereira BM. Análise epidemiológica e espacial dos casos de sífilis gestacional e congênita. Saúde e Debate. 2019;43(123):1145-1158. DOI: 10.1590/0103-1104201912313.

Wong NS, Chen L, Tucker JD, Zhao P, Goh BT, Poon CM, et al. Distribution of reported syphilis cases in South China: spatiotemporal analysis. Sci Rep. 2018; 14;8(1). DOI: 10.1038/s41598-018-27173-y.

Salway T, Gesink D, Lukac C, Roth D, Ryan V, Mak S, et al. Spatial-Temporal Epidemiology of the Syphilis Epidemic in Relation to Neighborhood-Level Structural Factors in British Columbia, 2005-2016. Sex Transm Dis. 2019 Sep;46(9):571-578. DOI: 10.1097/OLQ.0000000000001034.

Padovani C, Oliveira RR, Pelloso SM. Syphilis in during pregnancy: association of maternal and perinatal characteristics in a region of southern Brazil. Rev. Latino-Am. Enfermagem. 2018;26:e3019. DOI: 10.1590/1518-8345.2305.3019.

IBGE. Instituto Brasileiro de Geografia e Estatística. Cidades e estados - Paraná. 2020. Disponível em: https://cidades.ibge.gov.br/brasil/pr/panorama. Acesso em: 10 nov. 2021.

Getis A, Ord JK. The analysis of spatial association by use of distance statistics. Geographical analysis. 1992;24(3):189-206. DOI: 10.1111/j.1538-4632.1992.tb00261.x.

Instituto de Pesquisa de Sistemas Ambientais (Esri). HOW Hot Spot Analysis (Getis-Ord Gi*) works. Disponível em: https://pro.arcgis.com/en/pro-app/latest/tool-reference/spatial-statistics/h-how-hot-spot-analysis-getis-ord-gi-spatial-stati.htm. Acesso em: 17 out. 2021.

Nunes PS, Guimarães RA, Rosado LEP, Marinho TA, Aquino EC, Turchi MD. Temporal trend and spatial distribution of syphilis in pregnancy and congenital syphilis in Goiás, Brazil, 2007-2017: na ecological study. Epidemiol. Serv. Saúde [Internet]. 2021; 30(1): e2019371. DOI: 10.1590/S1679-49742021000100002.

Korenromp EL, Rowley J, Alonso M, Mello MB, Wijesooriya NS, Mahiané SG, et al. Global burden of maternal and congenital syphilis and associated adverse birth outcomes-Estimates for 2016 and progress since 2012. PLoS One. 2019;14(2):e0211720. DOI: 10.1371/journal.pone.0211720.

Menegazzo LS, Toldo MKS, Souto AS. A recrudescência da sífilis congênita. Arquivos Catarinenses de Medicina, 2018; 47 (1): 2-10. DOI: 10.1590/2317-6431-2015-1629.

Barimacker SV, Zocche DAA, Zanatta EA, Junior JDR, Korb A. Construction of a nursing flochartr and protocol for syphilis management in primary health care. Cienc Cuid Saude, 2022; 21 (1). DOI: 10.4025/ciencuidsaude.v21i0.59856.

Slutsker JS, Hennessy RR, Schillinger JA. Factors Contributing to Congenital Syphilis Cases - New York City, 2010-2016. MMWR Morb Mortal Wkly Rep. 2018;67(39):1088-1093. DOI: 10.15585/mmwr.mm6739a3.

Manolescu LSC, Boeru C, Caruntu C, Dragomirescu CC, Goldis M, Jugulete G, Marin M, Popa GL, Preda M, Radu MC, Popa MI. A Romanian experience of syphilis in pregnancy and childbirth. Midwifery. 2019;78;58-63. DOI: 10.1016/j.midw.2019.07.018.

Almeida RAAS, Corrêa RGCF, Rolim ILTP, Hora JM, Linard AG, Coutinho NPS, Oliveira PS. Knowledge of adolescents regarding sexually transmitted infections and pregnancy. Rev. Bras. Enferm. 2017;70(5):1033-1039. DOI: 10.1590/0034-7167-2016-0531.

Campos CO, Campos CO. Abordagem diagnóstica e terapêutica da sífilis gestacional e congênita: revisão narrativa. Rev Eletrônica Acervo Saúde. 2020;53. DOI: 10.25248/reas.e3786.2020.

Galvis AE, Arrieta A. Congenital Syphilis: A U.S. Perspective. Children. 2020;7(203). DOI: 10.3390/children7110203.

Teixeira LO, Belarmino V, Gonçalves CV, Mendoza-Sassi RA. Tendência temporal e distribuição espacial da sífilis congênita no estado do Rio Grande do Sul entre 2001 e 2012. Ciên. Saúde Colet. 2018;23(8):2587-2597. DOI: 10.1590/1413-81232018238.25422016.

Paiva KM, Silveira DS, Besen E, Moreira E, Corrêa VP, Hillesheim D, Hass P. Perfil epidemiológico da sífilis materna e congênita em Florianópolis, 2016-2017. Braz. J. of Develop. 2020;6(8):54750-54760. DOI: 10.34117/bjdv6n8-042.

Costa AWS, Freitas AS, Lopes KFAL. Epidemiologia da sífilis gestacional no Estado do Maranhão de 2015 a 2019. Rev Cereus. 2021;13(1). DOI: 10.18605/2175-7275/cereus.v13n1p52-61.

Vieira ISA, Caldas MLLS, Medeiros HRL, Lima TNFA, Berezin EM. Características epidemiológicas dos casos de sífilis congênita no Estado da Paraíba. Res., Soc. Dev. 2021;10(4). DOI: 10.33448/rsd-v10i4.13511.

Paraná. Secretaria de Estado da Saúde do Paraná. Plano Estadual de Saúde Paraná 2016-2019 – Curitiba: SESA, 2016. 200 p. Disponível em: https://www.conass.org.br/pdf/planos-estaduais-de-saude/PR_PlanoEstadualSaude2016MioloAlt.pdf. Acesso em: 15 out, 2022.

Araújo MAL, Andrade RFV, Barros VL, Bertoncini PMRP. Factors associated with unfavorable outcomes caused by Syphilis infection in pregnancy. Rev Bras Saúde Mater Infant. 2019;19(2)421-429. DOI: 10.1590/1806-93042019000200009.

Arjona, FBS. Sistemas de informações geográficas: usos e aplicações na área da saúde. Técnico de vigilância em saúde: fundamentos. 2017;2:113-136. Disponível em: https://www.arca.fiocruz.br/bitstream/handle/icict/39908/T%E9cnico%20de%20Vigil%E2ncia%20em%20Sa%FAde%20v.2%20-%20Sistemas%20de%20informa%E7%F5es%20geogr%E1ficas.pdf;jsessionid=B103469C5B3AFF2BA036499B64E37B50?sequence=2. Acesso em: 28 mar, 2023

Published
2023-09-08
How to Cite
Cortez, M. P., Scholze, A. R., Oliveira, R. R. de, Moreira, R. C., Araújo, K. H. P., & Melo, E. C. (2023). Spatio-temporal evolution of gestational and congenital syphilis in the state of Paraná. Ciência, Cuidado E Saúde, 22. https://doi.org/10.4025/ciencuidsaude.v22i0.66013
Section
Original articles