Training at different intensities and biomarkers of oxidative stress and glucose metabolism in skeletal muscle of rats - doi: 10.4025/reveducfis.v21i4.8538

Abstract

This study aimed to analyze the effects of physical training on biomarkers of oxidative stress and glucose metabolism in skeletal muscle of rats. Wistar rats (90 days) were trained by treadmill running at the speed equivalent to the metabolic transition aerobic-anaerobic (MT) and 25% above it (AT). As controls, rats maintained as sedentary (S) were used. There was no difference between the groups regarding the analyzed biomarkers of oxidative stress (amount of substances that react with thiobarbituric acid and catalase activity). Glucose uptake and Lactate production were reduced and Glucose oxidation and Synthesis of Glycogen were increased in the AT group compared to the others. The training at 25% above the aerobic-anaerobic transition intensity induced adaptations in muscle glucose metabolism in the absence of oxidative stress.