Comparison between tracheal anastomosis suture with absorbable synthetic thread and with nonabsorbable synthetic thread in rabbits

Abstract

Morphological and morphometric aspects of tracheal anastomosis in rabbits sutured with two absorbable synthetic threads and two nonabsorbable synthetic threads were compared in this study. The animals were divided into three equal groups of twenty-four individuals (A, B, C), for post-operation studies on the 7^th, 14^th and 28^th day. Each group was subdivided into four equal subgroups of six animals. After the excision of three cartilaginous rings, the tracheal anastomosis was sutured with polygalactine 910, polydioxan, polypropylene and polyester thread. The macroscopic examination verified a tracheal fistula on the seventh postoperation day in the anastomosis sutured with polyester. Cicraticial stenosis was most intensive and frequent with polyester and polydioxan threads in all the periods observed. On the fourteenth and twenty-eighth post-operation days, the optical microscopy revealed a chronic inflammatory reaction with higher intensity in sutures with polyester, polydioxan and polypropylene with a clear correlation between intense chronic inflammatory reaction and the macroscopic bad results observed in the anastomoses sutured with such threads. The final results lead to the conclusion that polygalactine 910 provided the best cicratization for tracheal anastomosis in rabbits, followed by polypropylene. Polydioxan and polyester threads provided the worst anastomosis cicratization