Atividade antibacteriana de extratos do caule de Cedrela fissilis Vell. (Meliaceae)

Diógenes Aparício Garcia Cortez; Lúcia Elaine Ranieri Cortez; Tânia Ueda Nakamura; Celso Vataru Nakamura

doi:10.4025/actascihealthsci.v20i0.4483

Antibacterian activity of extracts from wood of Cedrela fissilis Vell. (Meliaceae)

Authors

Diógenes Aparício Garcia Cortez UEM Author
Lúcia Elaine Ranieri Cortez UNIPAR Author
Tânia Ueda Nakamura UEM Author
Celso Vataru Nakamura UEM Author

DOI:

https://doi.org/10.4025/actascihealthsci.v20i0.4483

Keywords:

antimicrobiano, campesterol, Cedrela fissilis Vell., estigmasterol, Meliaceae, sitosterol

Abstract

Cedrela fissilis Vell. (Meliaceae) is a native tree found in forests of the state of Paraná, Brazil, and used in folk medicine as astringent and emetic substance against leukorrhea and in the washing of ulcers and wounds. Extracts of different polarity obtained from the stem were used to evaluate its antimicrobial activity against Staphylococcus aureus and Escherichia coli. Hexane extract yielded a mixture of sitosterol (50,40%), stigmasterol (21,70%) and campesterol (22,80%) which showed minimal inhibitory concentration (MIC) of 0,5mg/mL against Staphylococcus aureus.

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Author Biography

Diógenes Aparício Garcia Cortez, UEM

Possui graduação em Farmácia Bioquímica pela Universidade de São Paulo (1974), mestrado em Química pela Universidade Federal de São Carlos (1988) e doutorado em Química pela Universidade Federal de São Carlos (1993). Pós-Doutorado em farmacognosia na Universite de Lausanne (Suiça) (1997). Atualmente é professor Associado da Universidade Estadual de Maringá, departamento de farmácia e farmacologia. Tem experiência na área de Farmácia, com ênfase em Farmacognosia, atuando principalmente nos seguintes temas: fitoquímica, controle de qualidade, validação de fitoterápicos, antimicrobianos, kielmeyera coriacea, xantonas, atividades biológicas e piperaceae Currículo Lattes

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PDF (Portuguese)

Published

2008-07-21

Issue

Vol. 20 (1998)

Section

Health Sciences

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How to Cite

Cortez, D. A. G., Cortez, L. E. R., Nakamura, T. U., & Nakamura, C. V. (2008). Antibacterian activity of extracts from wood of Cedrela fissilis Vell. (Meliaceae). Acta Scientiarum. Health Sciences, 20, 243-245. https://doi.org/10.4025/actascihealthsci.v20i0.4483