PERIODONTAL DISEASE AS A RISK FACTOR FOR CARDIOVASCULAR DISEASE: LITERATURE REVIEW
Abstract
Introduction: recent studies have shown that there is an association between periodontal disease and cardiovascular disease due to chronic systemic inflammation that it generates in the individual. Objectives: to
compile scientific articles that confirm this association. Methods: the PUBMed database was used to search for articles, and a total of 551 publications were found in the last 5 years and 14 articles were selected. Results: show that levels of inflammatory cytokines were higher after the induction of periodontal disease, which may contribute to endothelial dysfunction. Also painful, the activation of polymorphonuclear cells is greater in patients with periodontal disease, which indicates a systemic inflammatory effect, from local inflammation. And finally, that the inflammatory process triggered by lipopolysaccharides from bacteria, increases the severity of periodontitis, the magnitude of inflammation and induces the formation of atherosclerotic plaque. Conclusion: periodontal disease promotes chronic systemic inflammation, capable of interfering with the cardiovascular system. Therefore, it should be addressed as a risk factor for cardiovascular disease.
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References
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