Efeito da Gymnema sylvestre na elevação da lipidemia após administração de gordura de origem animal em ratos wistar - DOI: 10.4025/actascibiolsci.v26i3.1602

Elizete Rosa dos Santos Silva; Roberto Barbosa Bazotte; Marcio dos Santos Vasconcelos; Márcia Regina Batista

doi:10.4025/actascibiolsci.v26i3.1602

**The influence of Gymnema sylvestre on the elevation of blood levels of lipids after administration of animal fat in male wistar rats** - DOI: 10.4025/actascibiolsci.v26i3.1602

Authors

Elizete Rosa dos Santos Silva UEM Author
Roberto Barbosa Bazotte UEM Author
Marcio dos Santos Vasconcelos UEM Author
Márcia Regina Batista UEM Author

DOI:

https://doi.org/10.4025/actascibiolsci.v26i3.1602

Keywords:

Gymnema sylvestre, absorção de lipídeos, ratos Wistar

Abstract

The aim of the present experiment was to investigate the influence of Gymnema sylvestre (Gs) on the elevation of blood levels of lipids after administration of animal fat in male Wistar rats (230–250g). The animals, which were fasted for 22h, were separated in five groups that received (8:00 a.m) intragastric administration of: 1) 2ml of pork fat Batavo® /kg of body weight (PFB); 2) PFB+500mg/kg of Gs body weight (Gs 500mg); 3) PFB + 1g/kg of Gs body weight (Gs 1 g); 4) Gs 500mg; 5) Gs 1g. The animals were sacrificed 30min after the administration of these substances. No significant differences were verified in the serum concentration of total lipids, triglycerides and cholesterol in the animals, which received PBF in the presence or absence of Gs 500mg or Gs 1g. Therefore, the results showed that Gs could not affect the intestinal absorption of lipids

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Author Biography

Márcia Regina Batista, UEM

possui graduação em Farmácia pela Universidade Estadual de Maringá (1984) , mestrado em Ciências Biológicas (Biologia Celular) pela Universidade Estadual de Maringá (1995) , doutorado em Ciências (Fisiologia Humana) pela Universidade de São Paulo (1999) e pos-doutorado pela Vanderbilt University (2004) . Atualmente é Professor Adjunto Nível C da Universidade Estadual de Maringá. Tem experiência na área de Fisiologia , com ênfase em Fisiologia de Órgãos e Sistemas. Atuando principalmente nos seguintes temas: Neoglicogênese hepática, Restrição alimentar Currículo Lattes

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Published

2008-04-01

Issue

Vol. 26 No. 3 (2004)

Section

Biology Sciences

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How to Cite

The influence of Gymnema sylvestre on the elevation of blood levels of lipids after administration of animal fat in male wistar rats - DOI: 10.4025/actascibiolsci.v26i3.1602. (2008). Acta Scientiarum. Biological Sciences, 26(3), 365-367. https://doi.org/10.4025/actascibiolsci.v26i3.1602