Efeito mutagênico da água natural (poço, rios Ficha e Minas Gerais, próximos Ã  cidade de Ubiratã, Estado do Paraná, Brasil) em sistema teste animal - DOI: 10.4025/actascibiolsci.v26i1.1665

Maria Fernanda P. Tomasi Baldez da Silva; Gisele Pezente Ferrari; Fabiana de Toledo; Carmem Lucia M. Sartori Cardoso da Rocha; Veronica Elisa Pimenta Vicentini

doi:10.4025/actascibiolsci.v26i1.1665

Mutagenic effect of fresh water (well, rivers Ficha and Minas Gerais, close to the town of Ubiratã, Paraná, Brazil) in the animal test system - DOI: 10.4025/actascibiolsci.v26i1.1665

Authors

Maria Fernanda P. Tomasi Baldez da Silva UEM Author
Gisele Pezente Ferrari UEM Author
Fabiana de Toledo UEM Author
Carmem Lucia M. Sartori Cardoso da Rocha UEM Author
Veronica Elisa Pimenta Vicentini UEM Author

DOI:

https://doi.org/10.4025/actascibiolsci.v26i1.1665

Keywords:

mutagênese, água natural, ratos Wistar

Abstract

Intense industrial development and population growth have been altering the quality of water and innumerous studies have been undertaken to analyze their effects on humans. Due to rivers contamination with agrotoxics, herbicides, pesticides, excess of farming chemical additives and through sewers spilling not properly treated industrial waste, investigating cytotoxic and mutagenic activity of river water becomes all-important. Bone marrow cells of Wistar rats (Rattus norvegicus), treated in vivo, through gavage, in subchronic treatment (7 days), were used as experimental animal test system to investigate the effects of well water and water from the rivers Ficha and Minas Gerais, close to the municipality of Ubiratã, State of Paraná, southern Brazil. Cell division index and metaphase chromosomes were analyzed. The statistical analysis showed that the experiment's water failed to alter cell division cycle of Wistar rats and did not increase number of chromosome aberrations. No cytotoxic and clastogenic effects ensued from this treatment

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Author Biography

Veronica Elisa Pimenta Vicentini, UEM

possui graduação em Ciências Biológicas pela Faculdade de Filosofia Ciências e Letras de Ribeirão Preto-USP (1977), Mestrado em Genética pela Faculdade de Medicina de Ribeirão Preto-USP (1984) e Doutorado Em Genética pela Faculdade de Medicina de Ribeirão Preto-USP (1992). Atualmente é Professor Associado C (TIDE) da Universidade Estadual de Maringá-PR. Tem experiência na área de Genética, com ênfase em Efeitos Citogenéticos, Mutagênicos e Antimutagênicos de Plantas Medicinais, Medicamentos Sintéticos e Ãguas de diferentes fontes, atuando principalmente nos seguintes temas: antimutagênese, mutagênese, citogenética, rato, cebola, plantas medicinais, drogas farmacológicas sintéyicas e águas (mina, poço, rio, efluentes) Currículo Lattes

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Published

2008-04-01

Issue

Vol. 26 No. 1 (2004)

Section

Biology Sciences

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How to Cite

Mutagenic effect of fresh water (well, rivers Ficha and Minas Gerais, close to the town of Ubiratã, Paraná, Brazil) in the animal test system - DOI: 10.4025/actascibiolsci.v26i1.1665. (2008). Acta Scientiarum. Biological Sciences, 26(1), 101-105. https://doi.org/10.4025/actascibiolsci.v26i1.1665