Avaliação da população de neurônios mioentéricos NADPH-diaforase positivos do corpo do estômago de ratos com diabetes crônico induzido pela estreptozootocina - DOI: 10.4025/actascibiolsci.v26i1.1667

Cristina Elena Prado Teles Fregonesi; Sônia Lucy Molinari; Marcílio Hubner de Miranda Neto

doi:10.4025/actascibiolsci.v26i1.1667

Evaluation of the population of NADPH-diaphorase positive myenteric neurons from the body of the stomach of diabetic rats induced by streptozotocin - DOI: 10.4025/actascibiolsci.v26i1.1667

Authors

Cristina Elena Prado Teles Fregonesi UNESP Author
Sônia Lucy Molinari UEM Author
Marcílio Hubner de Miranda Neto UEM Author

DOI:

https://doi.org/10.4025/actascibiolsci.v26i1.1667

Keywords:

diabetes, plexo mioentérico, neurônios nitrérgicos, estômago de ratos

Abstract

The aim of this study was to analyze the morphoquantitative features of the nitrergic myenteric neurons from the body of the stomach of diabetic rats. The body of the stomach of five normoglicemic rats and of five diabetic rats were prepared as whole-mounts stained by the histochemical technique of NADPH-diaphorase. Decreased body weight and increased daily ingestion of water, fast glicemia and glycated hemoglobin were verified in diabetic animals. According to the data obtained, significant difference in the density of nitrergic neurons was not observed between the two groups, but the areas of the neuronal cell body profiles in the diabetic rats were significantly larger. Results showed that the streptozotocin that induced diabetes does not accelerate the death of the nitrergic neurons, but increases the expression of these cells

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Author Biography

Cristina Elena Prado Teles Fregonesi, UNESP

Possui graduação em Fisioterapia pela UNESP - Universidade Estadual Paulista Júlio de Mesquita Filho (1989), mestrado em Ciências Biológicas (Biologia Celular) pela Universidade Estadual de Maringá (1997), doutorado em Ciências Biológicas (Biologia Celular) pela Universidade Estadual de Maringá (2003), Especialização em Terapia Manual e Técnicas Osteopáticas pelo Instituto Docusse de Terapia Manual em parceria com a Faculdade Estadual de Educação Física e Fisioterapia de Jacarezinho (2005) e Aperfeiçoamento em RPG pelo Instituto Philippe Souchard (2005). Atualmente é professor assistente doutor da UNESP - Universidade Estadual Paulista Júlio de Mesquita Filho. Tem experiência na área de Fisioterapia e Terapia Ocupacional, com ênfase em Fisioterapia, atuando principalmente nos seguintes temas: Neuropatia Periférica (diabetes mellitus e hanseníase); Terapia Manual/Osteopatia; Reeducação Postural Global Currículo Lattes

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Published

2008-04-01

Issue

Vol. 26 No. 1 (2004)

Section

Biology Sciences

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How to Cite

Evaluation of the population of NADPH-diaphorase positive myenteric neurons from the body of the stomach of diabetic rats induced by streptozotocin - DOI: 10.4025/actascibiolsci.v26i1.1667. (2008). Acta Scientiarum. Biological Sciences, 26(1), 107-112. https://doi.org/10.4025/actascibiolsci.v26i1.1667