Pharmacovigilance at Regional University Hospital in Maringá, PR

Abstract

This work describes the investigative experience of suspected cases of adverse drug reactions reported at Regional University Hospital of Maringá. Data collection and home visit procedures are described as both - a way to clarify the diagnosis; a way to provide these people and their family information about using and storage of medication. From 1996 to 2000, 316 cases of suspicious adverse drug reactions were registered. From the total, in only 105 cases the home visit was carried out. The application of the Algorithm of Naranjo allowed classifying the suspicious cases in evident cases (4,8%), probable (56,7%), possible (34,6%) and doubtful (3,9%). It was also verified that most of the notifications originate from active search in medical files and that the spontaneous reporting are still few. Therefore, strategies should be developed to increase spontaneous reporting of suspected adverse reaction to drugs by health professionals, independently of the seriousness or unusualness of the suspected reaction